Chemical Structure / July 18, 2018 / Ansley Conrad
Benzoyl peroxide is effective for reducing the number and severity of acne lesions. BPO has a bactericidal effect on Propionibacterium acnes bacteria associated with acne and does not induce antibiotic resistance. It may be combined with salicylic acid, sulfur, erythromycin or clindamycin (antibiotics), or adapalene (a synthetic retinoid). Two common combination drugs include benzoyl peroxideclindamycin and adapalenebenzoyl peroxide, an unusual formulation considering most retinoids are deactivated by peroxides. Combination products such as benzoyl peroxideclindamycin and benzoyl peroxidesalicylic acid appear to be slightly more effective than benzoyl peroxide alone for the treatment of acne lesions.
Carbon tetrabromide (CBr4) is most commonly used as a reagent for converting alcohols to bromides in Appel reactions. Carbon tetrabromide is generally not used as a solvent, whereas its chloro analogue, carbon tetrachloride (CCl4), sees frequent use as a solvent.
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