Chemical Structure / July 20, 2018 / Isabelle Vinson
The original synthesis of cinnamic acid involves the Perkin reaction, which entails the base-catalysed condensation of acetic anhydride and benzaldehyde. Rainer Ludwig Claisen (1851–1930) described the synthesis of cinnamate esters by the reaction of benzaldehyde and esters. The reaction is known as the Aldol condensation (with accompanying hydrolysis of the anhydride).
relies heavily on using NMR spectroscopy is NMR Chemical Shifts of Common Laboratory Solvents as Trace Impurities
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