Chemical Structure / July 21, 2018 / Serena Calhoun
Benzyl chloride is used as a chemical intermediate in the manufacture of certain dyes and pharmaceutical products and as a photographic developer. The acute (short-term) effects of benzyl chloride from inhalation exposure in humans consist of severe irritation of the upper respiratory tract, skin, eyes, and mucous membranes, and lung damage along with pulmonary edema (fluid in lungs).
Ionized silver atoms catalyze the formation of disulfide bonds leading to protein structural changes and inactivating thiol-containing enzymes; silver ions may also intercalate DNA thereby interfering with replication and transcription of bacteria. As a competitive inhibitor of para-aminobenzoic acid (PABA), sulfadiazine inhibits bacterial dihydropteroate synthase, thereby resulting in disruption of folic acid metabolism and ultimately DNA synthesis.
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