Chemical Structure / July 18, 2018 / Serena Calhoun
It is widely used in biochemistry for the precipitation of macromolecules, such as proteins, DNA, and RNA. TCA and DCA are both used in cosmetic treatments (such as chemical peels and tattoo removal) and as topical medication for chemoablation of warts, including genital warts. It can kill normal cells as well. It is considered safe for use for this purpose during pregnancy.
Isoquinolines are a class of compounds (benzopyridines) which are used in medical contexts (such as the anesthetic dimethisoquin, the antihypertensive debrisoquine, and the vasodilator papaverine) and in other areas (such as disinfectant N-laurylisoquinolinium bromide). Isoquinoline itself is efficiently prepared using the Pomeranz-Fritsch reaction, but can also be prepared from benzylamine and glyoxal acetal by an analogous approach known as the Schlittler-Muller modification to the Pomeranz-Fritsch reaction. This modification can also be used for preparing substituted isoquinolines.
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